What is stem cell therapy?
Stem cell therapy is a form of regenerative medicine designed to fix damaged cells within the body by reducing inflammation and modulating the immune system. This phenomenon makes stem cell therapy a practical treatment option for a variety of medical conditions. Stem cell therapies have been used to treat autoimmune, inflammatory, neurological, orthopedic conditions and traumatic injuries with studies performed on use for Crohn's disease, Multiple Sclerosis, Lupus, COPD, Parkinson's, ALS, Stroke recovery and more.
While stem cell therapy does not necessarily provide a cure for these disorders, the premise is to allow the body to heal itself well enough to alleviate the symptoms of the disorders for extended periods. In some cases, this effect can considerably improve the quality of life for patients as well as delay disease progression.
Where do stem cells originate from?
Stem cells can be acquired from many different sources. These include adipose (fat tissue), umbilical cord tissue, placental tissue, umbilical cord blood, or bone marrow.
How are stem cells administered?
Stem cells can be administered in a range of ways; IV Stem Cell Therapy (Intravenous administration), Intrathecal (directly into the spinal canal), Site injections into problem areas (Knee, hips, hands, etc.).
How does stem cell therapy work?
Mesenchymal stem cells utilize their self-renewal, immunomodulatory, anti-inflammatory, signaling, and differentiation properties to influence positive change within the body. Mesenchymal stem cells (MSCs) also have the ability to self-renew by dividing and turning into various specialized cell types present in a specific tissue or organ. Mesenchymal stem cells are adult stem cells, indicating they present no ethical problems, MSCs are not sourced from embryonic material.
Stem cells target inflammation
The therapeutic uses of stem cells as a potential treatment for a range of conditions has been immensely explored, the amount of clinical trials performed with Mesenchymal Stem Cells has increased significantly over the past few years.
Stem cells have a special, innate quality that attracts them to inflammation in the body. Studies have shown that stem cells can regenerate damaged or diseased tissues, reduce inflammation and modulate the immune system promoting better health and quality of life. Mesenchymal stem cells do this by affecting tissue repair using paracrine effects (cell signaling in order to change the behaviour of existing cells) or direct cell-to-cell contact.
What are stem cells?
Stem cells are the body's raw materials-- cells from which all other cells with specialized functions are developed. Mesenchymal stem cells are adult stem cells that have self-renewal, immunomodulatory, anti-inflammatory, signaling, and differentiation qualities. Mesenchymal stem cells (MSCs), self renewal ability is defined by their ability to divide and become numerous specialized cell types present in a particular tissue or organ.
Mesenchymal stem cells (MSCs) can be sourced from a variety of tissues including adipose tissue (fat), bone marrow, umbilical cord tissue, blood, liver, dental pulp, and also skin.
MSCs are widely used in the treatment of numerous diseases due to their self-renewable, differentiation, anti-inflammatory, and immunomodulatory qualities. In-vitro (performed in a laboratory setting) and in-vivo (occurring in a living organism) studies have supported the understanding mechanisms, safety, and efficacy of MSC therapy in clinical applications.
Mesenchymal stem cells have the ability to turn into new types of cells
A stem cell can turn into many different cell types in the body. The process of stem cells maturing into new kinds of cells is called differentiation. This process is the most critical aspect of stem cell therapies, as the cells become the kind of cells required for one's body to heal.
Stem cells are also self-replicating; this ability allows the cells to multiply into identical copies of themselves. For instance, if stem cells were used to treat a neurological injury, cells administered during treatment could turn into nerve cells, and then replicate to create significantly more nerve cells on their own. This ability to replicate substantially improves the effectiveness of stem cell therapies over time.
How is stem cell therapy utilized?
Stem cell therapy might be able to treat orthopedic, inflammatory, autoimmune and neurological disorders, with studies performed on use for Crohn's Disease, Multiple Sclerosis, Lupus, COPD, Parkinson's, ALS, Stroke recovery and more.
Stem cells do not necessarily offer a cure for these conditions. The goal is allowing the body to heal itself well enough to mitigate the symptoms of the disorders for extended periods. In some cases, this alone allows for a considerable increase in quality of life for patients.
Will the body reject stem cells?
Cord-tissue obtained mesenchymal stem cells do not have any risk of rejection within the body. They are youthful, immune-privileged, undifferentiated cells that have no rejection in the body because they have yet to be "claimed.".
There are no blood products related to them either, eliminating the need for a donor match; they are universally accepted. These cells seek out inflammation in the body and start to heal the damaged tissue. Mesenchymal cord tissue-derived stem cells have been administered thousands of times at clinics worldwide without instances of rejection.